Development of chiral metal amides as highly reactive catalysts for asymmetric [3 + 2] cycloadditions
نویسندگان
چکیده
Highly efficient catalytic asymmetric [3 + 2] cycloadditions using a chiral copper amide are reported. Compared with the chiral CuOTf/Et3N system, the CuHMDS system showed higher reactivity, and the desired reactions proceeded in high yields and high selectivities with catalyst loadings as low as 0.01 mol %.
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